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Kinetin riboside
CAS No. 4338-47-0
Kinetin riboside ( N6-Furfuryladenosine;FAdo )
Catalog No. M14476 CAS No. 4338-47-0
A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 27 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameKinetin riboside
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NoteResearch use only, not for human use.
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Brief DescriptionA cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines.
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DescriptionA cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines; inhibits MiPaCa-2 cell proliferation with IC50 of 0.27 uM; induceds marked suppression of CCND2 transcription and rapidly suppresses cyclin D1 and D2 protein expression in primary myeloma cells and tumor lines, causing cell cycle arrest, tumor cell-selective apoptosis, and inhibition of myeloma growth in xenografted mice; also can activate PINK1 in cells independent of mitochondrial depolarization.
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SynonymsN6-Furfuryladenosine;FAdo
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number4338-47-0
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Formula Weight347.33
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Molecular FormulaC15H17N5O5
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 29 mg/mL
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SMILESO[C@H]1[C@H](N2C=NC3=C(NCC4=CC=CO4)N=CN=C23)O[C@H](CO)[C@H]1O
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Chemical NameAdenosine, N-(2-furanylmethyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Osgerby L, et al. J Med Chem. 2017 Apr 27;60(8):3518-3524.
2. Tiedemann RE, et al. J Clin Invest. 2008 May;118(5):1750-64.
3. Hertz NT, et al. Cell. 2013 Aug 15;154(4):737-47.
4. Choi BH, et al. J Biol Chem. 2010 Mar 26;285(13):9770-9.
2. Tiedemann RE, et al. J Clin Invest. 2008 May;118(5):1750-64.
3. Hertz NT, et al. Cell. 2013 Aug 15;154(4):737-47.
4. Choi BH, et al. J Biol Chem. 2010 Mar 26;285(13):9770-9.
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